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WASP family proteins and formins compete in pseudopod- and bleb-based migration
Actin pseudopods induced by SCAR/WAVE drive normal migration and chemotaxis in eukaryotic cells. Cells can also migrate using blebs, in which the edge is driven forward by hydrostatic pressure instead of actin. In Dictyostelium discoideum, loss of SCAR is compensated by WASP moving to the leading ed...
Autores principales: | Davidson, Andrew J., Amato, Clelia, Thomason, Peter A., Insall, Robert H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800805/ https://www.ncbi.nlm.nih.gov/pubmed/29191847 http://dx.doi.org/10.1083/jcb.201705160 |
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