Control of microtubule dynamics using an optogenetic microtubule plus end–F-actin cross-linker

We developed a novel optogenetic tool, SxIP–improved light-inducible dimer (iLID), to facilitate the reversible recruitment of factors to microtubule (MT) plus ends in an end-binding protein–dependent manner using blue light. We show that SxIP-iLID can track MT plus ends and recruit tgRFP-SspB upon...

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Detalles Bibliográficos
Autores principales: Adikes, Rebecca C., Hallett, Ryan A., Saway, Brian F., Kuhlman, Brian, Slep, Kevin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800807/
https://www.ncbi.nlm.nih.gov/pubmed/29259096
http://dx.doi.org/10.1083/jcb.201705190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800807/
https://www.ncbi.nlm.nih.gov/pubmed/29259096
http://dx.doi.org/10.1083/jcb.201705190

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