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Control of microtubule dynamics using an optogenetic microtubule plus end–F-actin cross-linker
We developed a novel optogenetic tool, SxIP–improved light-inducible dimer (iLID), to facilitate the reversible recruitment of factors to microtubule (MT) plus ends in an end-binding protein–dependent manner using blue light. We show that SxIP-iLID can track MT plus ends and recruit tgRFP-SspB upon...
Autores principales: | Adikes, Rebecca C., Hallett, Ryan A., Saway, Brian F., Kuhlman, Brian, Slep, Kevin C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800807/ https://www.ncbi.nlm.nih.gov/pubmed/29259096 http://dx.doi.org/10.1083/jcb.201705190 |
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