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dTBC1D7 regulates systemic growth independently of TSC through insulin signaling

The insulin signaling pathway plays key roles in systemic growth. TBC1D7 has recently been identified as the third subunit of the tuberous sclerosis complex (TSC), a negative regulator of cell growth. Here, we used Drosophila as a model system to dissect the physiological function of TBC1D7 in vivo....

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Detalles Bibliográficos
Autores principales: Ren, Suxia, Huang, Zengyi, Jiang, Yuqiang, Wang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800808/
https://www.ncbi.nlm.nih.gov/pubmed/29187524
http://dx.doi.org/10.1083/jcb.201706027