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miRNA suppression of a Notch repressor directs non-neuronal fate in Drosophila mechanosensory organs

Although there is abundant evidence that individual microRNA (miRNA) loci repress large cohorts of targets, large-scale knockout studies suggest that most miRNAs are phenotypically dispensable. Here, we identify a rare case of developmental cell specification that is highly dependent on miRNA contro...

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Detalles Bibliográficos
Autores principales: Kavaler, Joshua, Duan, Hong, Aradhya, Rajaguru, de Navas, Luis F., Joseph, Brian, Shklyar, Boris, Lai, Eric C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800810/
https://www.ncbi.nlm.nih.gov/pubmed/29196461
http://dx.doi.org/10.1083/jcb.201706101