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N-Glycan–dependent protein folding and endoplasmic reticulum retention regulate GPI-anchor processing

Glycosylphosphatidylinositol (GPI) anchoring of proteins is a conserved posttranslational modification in the endoplasmic reticulum (ER). Soon after GPI is attached, an acyl chain on the GPI inositol is removed by post-GPI attachment to proteins 1 (PGAP1), a GPI-inositol deacylase. This is crucial f...

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Detalles Bibliográficos
Autores principales: Liu, Yi-Shi, Guo, Xin-Yu, Hirata, Tetsuya, Rong, Yao, Motooka, Daisuke, Kitajima, Toshihiko, Murakami, Yoshiko, Gao, Xiao-Dong, Nakamura, Shota, Kinoshita, Taroh, Fujita, Morihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800811/
https://www.ncbi.nlm.nih.gov/pubmed/29255114
http://dx.doi.org/10.1083/jcb.201706135