L1 retrotransposon antisense RNA within ASAR lncRNAs controls chromosome-wide replication timing

Mammalian cells replicate their chromosomes via a temporal replication program. The ASAR6 and ASAR15 genes were identified as loci that when disrupted result in delayed replication and condensation of entire human chromosomes. ASAR6 and ASAR15 are monoallelically expressed long noncoding RNAs that r...

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Detalles Bibliográficos
Autores principales: Platt, Emily J., Smith, Leslie, Thayer, Mathew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800813/
https://www.ncbi.nlm.nih.gov/pubmed/29288153
http://dx.doi.org/10.1083/jcb.201707082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800813/
https://www.ncbi.nlm.nih.gov/pubmed/29288153
http://dx.doi.org/10.1083/jcb.201707082

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