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Transfer and Metabolism of Cortisol by the Isolated Perfused Human Placenta

CONTEXT: Fetal overexposure to glucocorticoids in utero is associated with fetal growth restriction and is postulated to be a key mechanism linking suboptimal fetal growth with cardiovascular disease in later life. OBJECTIVE: To develop a model to predict maternal-fetal glucocorticoid transfer. We h...

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Detalles Bibliográficos
Autores principales: Stirrat, Laura I., Sengers, Bram G., Norman, Jane E., Homer, Natalie Z. M., Andrew, Ruth, Lewis, Rohan M., Reynolds, Rebecca M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800837/
https://www.ncbi.nlm.nih.gov/pubmed/29161409
http://dx.doi.org/10.1210/jc.2017-02140