SCD5 restored expression favors differentiation and epithelial-mesenchymal reversion in advanced melanoma

Our previous data supported a role for the Stearoyl-CoA desaturase (SCD5) in protection against malignancy, whereby it appears to functionally modify tumor stroma impairing tumor spread. SCD5 is significantly expressed in primary melanoma, but becomes barely detectable at tumor advanced stages. Look...

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Detalles Bibliográficos
Autores principales: Puglisi, Rossella, Bellenghi, Maria, Pontecorvi, Giada, Gulino, Alessandro, Petrini, Marina, Felicetti, Federica, Bottero, Lisabianca, Mattia, Gianfranco, Carè, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800925/
https://www.ncbi.nlm.nih.gov/pubmed/29484133
http://dx.doi.org/10.18632/oncotarget.24085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800925/
https://www.ncbi.nlm.nih.gov/pubmed/29484133
http://dx.doi.org/10.18632/oncotarget.24085

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