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SCD5 restored expression favors differentiation and epithelial-mesenchymal reversion in advanced melanoma
Our previous data supported a role for the Stearoyl-CoA desaturase (SCD5) in protection against malignancy, whereby it appears to functionally modify tumor stroma impairing tumor spread. SCD5 is significantly expressed in primary melanoma, but becomes barely detectable at tumor advanced stages. Look...
Autores principales: | Puglisi, Rossella, Bellenghi, Maria, Pontecorvi, Giada, Gulino, Alessandro, Petrini, Marina, Felicetti, Federica, Bottero, Lisabianca, Mattia, Gianfranco, Carè, Alessandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800925/ https://www.ncbi.nlm.nih.gov/pubmed/29484133 http://dx.doi.org/10.18632/oncotarget.24085 |
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