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S100A9(+) MDSC and TAM-mediated EGFR-TKI resistance in lung adenocarcinoma: the role of RELB

BACKGROUND: Monocytic myeloid-derived suppressor cells (MDSCs), particularly the S100A9+ subset, has been shown initial clinical relevance. However, its role in EGFR-mutated lung adenocarcinoma, especially to EGFR-tyrosine kinase inhibitor (EGFR-TKI) is not clear. In a clinical setting of EGFR mutat...

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Detalles Bibliográficos
Autores principales: Feng, Po-Hao, Yu, Chih-Teng, Chen, Kuan-Yuan, Luo, Ching-Shan, Wu, Shen Ming, Liu, Chien-Ying, Kuo, Lu Wei, Chan, Yao-Fei, Chen, Tzu-Tao, Chang, Chih-Cheng, Lee, Chun-Nin, Chuang, Hsiao-Chi, Lin, Chiou-Feng, Han, Chia-Li, Lee, Wei-Hwa, Lee, Kang-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800931/
https://www.ncbi.nlm.nih.gov/pubmed/29484139
http://dx.doi.org/10.18632/oncotarget.24146