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Scaffolds that mimic antigen-presenting cells enable ex vivo expansion of primary T-cells
Therapeutic ex vivo T cell expansion is limited by low rates, and T-cell products of limited functionality. Here we describe a system that mimics natural antigen-presenting cells (APCs) and consists of a fluid lipid bilayer supported by mesoporous silica micro-rods. The lipid bilayer presents membra...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801009/ https://www.ncbi.nlm.nih.gov/pubmed/29334370 http://dx.doi.org/10.1038/nbt.4047 |