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Scaffolds that mimic antigen-presenting cells enable ex vivo expansion of primary T-cells

Therapeutic ex vivo T cell expansion is limited by low rates, and T-cell products of limited functionality. Here we describe a system that mimics natural antigen-presenting cells (APCs) and consists of a fluid lipid bilayer supported by mesoporous silica micro-rods. The lipid bilayer presents membra...

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Detalles Bibliográficos
Autores principales:	Cheung, Alexander S., Zhang, David K.Y., Koshy, Sandeep T., Mooney, David J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801009/ https://www.ncbi.nlm.nih.gov/pubmed/29334370 http://dx.doi.org/10.1038/nbt.4047

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