The Molecular Determinants of Small-Molecule Ligand Binding at P2X Receptors

P2X receptors are trimeric eukaryotic ATP-gated cation channels. Extracellular ATP—their physiological ligand—is released as a neurotransmitter and in conditions of cell damage such as inflammation, and substantial evidence implicates P2X receptors in diseases including neuropathic pain, cancer, and...

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Detalles Bibliográficos
Autores principales: Pasqualetto, Gaia, Brancale, Andrea, Young, Mark T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801290/
https://www.ncbi.nlm.nih.gov/pubmed/29456508
http://dx.doi.org/10.3389/fphar.2018.00058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801290/
https://www.ncbi.nlm.nih.gov/pubmed/29456508
http://dx.doi.org/10.3389/fphar.2018.00058

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