Identification of Single Nucleotide Non-coding Driver Mutations in Cancer

Recent whole-genome sequencing studies have identified millions of somatic variants present in tumor samples. Most of these variants reside in non-coding regions of the genome potentially affecting transcriptional and post-transcriptional gene regulation. Although a few hallmark examples of driver m...

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Detalles Bibliográficos
Autores principales: Gan, Kok A., Carrasco Pro, Sebastian, Sewell, Jared A., Fuxman Bass, Juan I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801294/
https://www.ncbi.nlm.nih.gov/pubmed/29456552
http://dx.doi.org/10.3389/fgene.2018.00016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801294/
https://www.ncbi.nlm.nih.gov/pubmed/29456552
http://dx.doi.org/10.3389/fgene.2018.00016

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