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Identification of Single Nucleotide Non-coding Driver Mutations in Cancer
Recent whole-genome sequencing studies have identified millions of somatic variants present in tumor samples. Most of these variants reside in non-coding regions of the genome potentially affecting transcriptional and post-transcriptional gene regulation. Although a few hallmark examples of driver m...
Autores principales: | Gan, Kok A., Carrasco Pro, Sebastian, Sewell, Jared A., Fuxman Bass, Juan I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801294/ https://www.ncbi.nlm.nih.gov/pubmed/29456552 http://dx.doi.org/10.3389/fgene.2018.00016 |
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