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An Uncoupling of Canonical Phenotypic Markers and Functional Potency of Ex Vivo-Expanded Natural Killer Cells

Recent advances in cellular therapies for patients with cancer, including checkpoint blockade and ex vivo-expanded, tumor-specific T cells, have demonstrated that targeting the immune system is a powerful approach to the elimination of tumor cells. Clinical efforts have also demonstrated limitations...

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Detalles Bibliográficos
Autores principales: Lieberman, Nicole A. P., DeGolier, Kole, Haberthur, Kristen, Chinn, Harrison, Moyes, Kara W., Bouchlaka, Myriam N., Walker, Kirsti L., Capitini, Christian M., Crane, Courtney A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801405/
https://www.ncbi.nlm.nih.gov/pubmed/29456538
http://dx.doi.org/10.3389/fimmu.2018.00150