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The Complement Binding and Inhibitory Protein CbiA of Borrelia miyamotoi Degrades Extracellular Matrix Components by Interacting with Plasmin(ogen)

The emerging relapsing fever spirochete Borrelia (B.) miyamotoi is transmitted by ixodid ticks and causes the so-called hard tick-borne relapsing fever or B. miyamotoi disease (BMD). More recently, we identified a surface-exposed molecule, CbiA exhibiting complement binding and inhibitory capacity a...

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Detalles Bibliográficos
Autores principales: Nguyen, Ngoc T. T., Röttgerding, Florian, Devraj, Gayatri, Lin, Yi-Pin, Koenigs, Arno, Kraiczy, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801413/
https://www.ncbi.nlm.nih.gov/pubmed/29456970
http://dx.doi.org/10.3389/fcimb.2018.00023