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Mineralocorticoid receptor antagonist in heart failure: Past, present and future perspectives

Aldosterone is involved in various deleterious effects on the cardiovascular system, including sodium and fluid retention, myocardial fibrosis, vascular stiffening, endothelial dysfunction, catecholamine release and stimulation of cardiac arrhythmias. Therefore, aldosterone receptor blockade may hav...

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Detalles Bibliográficos
Autores principales: Vizzardi, Enrico, Regazzoni, Valentina, Caretta, Giorgio, Gavazzoni, Mara, Sciatti, Edoardo, Bonadei, Ivano, Trichaki, Eleftheria, Raddino, Riccardo, Metra, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801434/
https://www.ncbi.nlm.nih.gov/pubmed/29450163
http://dx.doi.org/10.1016/j.ijchv.2014.03.005