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Mineralocorticoid receptor antagonist in heart failure: Past, present and future perspectives
Aldosterone is involved in various deleterious effects on the cardiovascular system, including sodium and fluid retention, myocardial fibrosis, vascular stiffening, endothelial dysfunction, catecholamine release and stimulation of cardiac arrhythmias. Therefore, aldosterone receptor blockade may hav...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801434/ https://www.ncbi.nlm.nih.gov/pubmed/29450163 http://dx.doi.org/10.1016/j.ijchv.2014.03.005 |