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Expanding Primary Metabolism Helps Generate the Metabolic Robustness To Facilitate Antibiotic Biosynthesis in Streptomyces

The expansion of the genetic repertoire of an organism by gene duplication or horizontal gene transfer (HGT) can aid adaptation. Streptomyces bacteria are prolific producers of bioactive specialized metabolites that have adaptive functions in nature and have found extensive utility in human medicine...

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Detalles Bibliográficos
Autores principales: Schniete, Jana K., Cruz-Morales, Pablo, Selem-Mojica, Nelly, Fernández-Martínez, Lorena T., Hunter, Iain S., Barona-Gómez, Francisco, Hoskisson, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801464/
https://www.ncbi.nlm.nih.gov/pubmed/29437921
http://dx.doi.org/10.1128/mBio.02283-17