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Expanding Primary Metabolism Helps Generate the Metabolic Robustness To Facilitate Antibiotic Biosynthesis in Streptomyces
The expansion of the genetic repertoire of an organism by gene duplication or horizontal gene transfer (HGT) can aid adaptation. Streptomyces bacteria are prolific producers of bioactive specialized metabolites that have adaptive functions in nature and have found extensive utility in human medicine...
Autores principales: | Schniete, Jana K., Cruz-Morales, Pablo, Selem-Mojica, Nelly, Fernández-Martínez, Lorena T., Hunter, Iain S., Barona-Gómez, Francisco, Hoskisson, Paul A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801464/ https://www.ncbi.nlm.nih.gov/pubmed/29437921 http://dx.doi.org/10.1128/mBio.02283-17 |
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