Contrasting roles of H3K4me3 and H3K9me3 in regulation of apoptosis and gemcitabine resistance in human pancreatic cancer cells

BACKGROUND: Pancreas ductal adenocarcinoma (PDAC) has the most dismal prognosis among all human cancers since it is highly resistant to chemotherapy, radiotherapy and immunotherapy. The anticipated consequence of all therapies is induction of tumor apoptosis. The highly resistance nature of PDACs to...

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Detalles Bibliográficos
Autores principales: Lu, Chunwan, Yang, Dafeng, Sabbatini, Maria E., Colby, Aaron H., Grinstaff, Mark W., Oberlies, Nicholas H., Pearce, Cedric, Liu, Kebin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801751/
https://www.ncbi.nlm.nih.gov/pubmed/29409480
http://dx.doi.org/10.1186/s12885-018-4061-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801751/
https://www.ncbi.nlm.nih.gov/pubmed/29409480
http://dx.doi.org/10.1186/s12885-018-4061-y

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