JNK3 phosphorylates Bax protein and induces ability to form pore on bilayer lipid membrane

Bax is a pro-apoptotic cytosolic protein. In this work native (unphosphorylated) and JNK3 phosphorylated Bax proteins are studied on artificial bilayer membranes for pore formation. Phosphorylated Bax formed pore on the bilayer lipid membrane whereas native one does not. In cells undergoing apoptosi...

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Detalles Bibliográficos
Autores principales: Gupta, Rajeev, Ghosh, Subhendu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801821/
https://www.ncbi.nlm.nih.gov/pubmed/29450140
http://dx.doi.org/10.1016/j.biopen.2017.02.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801821/
https://www.ncbi.nlm.nih.gov/pubmed/29450140
http://dx.doi.org/10.1016/j.biopen.2017.02.001

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