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Sleeping Beauty transposon integrates into non-TA dinucleotides

BACKGROUND: Sleeping Beauty transposon (SB) has become an increasingly important genetic tool for generating mutations in vertebrate cells. It is widely thought that SB exclusively integrates into TA dinucleotides. However, this strict TA-preference has not been rigorously tested in large numbers of...

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Detalles Bibliográficos
Autores principales: Guo, Yabin, Zhang, Yin, Hu, Kaishun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801840/
https://www.ncbi.nlm.nih.gov/pubmed/29445422
http://dx.doi.org/10.1186/s13100-018-0113-8