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CRISPR/Cas9-mediated target validation of the splicing inhibitor Pladienolide B

CRISPR/Cas9 system confers molecular immunity in archeal and bacterial species against invading foreign nucleic acids. CRISPR/Cas9 system is used for genome engineering applications across diverse eukaryotic species. In this study, we demonstrate the utility of the CRISPR/Cas9 genome engineering sys...

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Detalles Bibliográficos
Autores principales: Aouida, Mustapha, Eid, Ayman, Mahfouz, Magdy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801905/
https://www.ncbi.nlm.nih.gov/pubmed/29450134
http://dx.doi.org/10.1016/j.biopen.2016.02.001