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Fate of Antibody-Drug Conjugates in Cancer Cells
Antibody-Drug Conjugates (ADCs) are a class of cancer therapeutics that combines antigen specificity and potent cytotoxicity in a single molecule as they are comprised of an engineered antibody linked chemically to a cytotoxic drug. Four ADCs have received approval by the Food and Drug Administratio...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802061/ https://www.ncbi.nlm.nih.gov/pubmed/29409507 http://dx.doi.org/10.1186/s13046-017-0667-1 |