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Effects of intrathecal bupivacaine on the NR2B/CaMKIIα/CREB signaling pathway in the rat lumbar spinal cord

Neuraxial anesthesia produces an anesthetic-sparing, sedative effect. The mechanism underlying this effect potentially involves decreased spinal afferent input. However, the neurochemical mechanisms at the spinal level remain unknown. The N-methyl-D-aspartate receptor 2B subunit/calcium-calmodulin-d...

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Detalles Bibliográficos
Autores principales: Zhao, Liyan, Zhang, Yonghai, Yang, Fan, Zhu, Di, Li, Ningkang, Zhao, Li, Li, Na, Yu, Jianqiang, Ma, Hanxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802227/
https://www.ncbi.nlm.nih.gov/pubmed/29344649
http://dx.doi.org/10.3892/mmr.2018.8448