Cargando…

The CGRP receptor antagonist BIBN4096 inhibits prolonged meningeal afferent activation evoked by brief local K(+) stimulation but not cortical spreading depression-induced afferent sensitization

INTRODUCTION: Cortical spreading depression (CSD) is believed to promote migraine headache by enhancing the activity and mechanosensitivity of trigeminal intracranial meningeal afferents. One putative mechanism underlying this afferent response involves an acute excitation of meningeal afferents by...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Jun, Levy, Dan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer 2017
Materias:	Basic Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802320/ https://www.ncbi.nlm.nih.gov/pubmed/29430561 http://dx.doi.org/10.1097/PR9.0000000000000632

Ejemplares similares

The CGRP-Antagonist BIBN4096BS Discriminates between the Action of α- and β-CGRP In Vitro
por: Wu, Dongmei, et al.
Publicado: (2001)

Functional Characterisation of the CGRP Antagonist BIBN4096BS, in SK-N-MC Cells
por: Schindler, Marcus, et al.
Publicado: (2001)

Study of Cgrp-Receptors in Human Isolated Middle Meningeal Arteries Using Bibn4096Bs, Compound 1, and HαCgrp(8-37)
por: Razzaque, Z., et al.
Publicado: (2001)

Non-peptidic antagonists of the CGRP receptor, BIBN4096BS and MK-0974, interact with the calcitonin receptor-like receptor via methionine-42 and RAMP1 via tryptophan-74
por: Miller, Philip S., et al.
Publicado: (2010)

Cortical Spreading Depression Promotes Persistent Mechanical Sensitization of Intracranial Meningeal Afferents: Implications for the Intracranial Mechanosensitivity of Migraine
por: Zhao, Jun, et al.
Publicado: (2016)

Trigeminal afferents sense locomotion-related meningeal deformations
por: Blaeser, Andrew S., et al.
Publicado: (2022)

Sensitization of meningeal afferents to locomotion-related meningeal deformations in a migraine model
por: Blaeser, Andrew S, et al.
Publicado: (2023)

Anatomical distribution of CGRP-containing lumbosacral spinal afferent neurons in the mouse uterine horn
por: Dodds, Kelsi N., et al.
Publicado: (2022)

Calcitonin gene-related peptide receptor antagonist BIBN4096BS regulates synaptic transmission in the vestibular nucleus and improves vestibular function via PKC/ERK/CREB pathway in an experimental chronic migraine rat model
por: Tian, Ruimin, et al.
Publicado: (2022)

Inhibition of Parkinsonian tremor with cutaneous afferent evoked by transcutaneous electrical nerve stimulation
por: Hao, Man-Zhao, et al.
Publicado: (2017)

TLR4 Signaling Selectively and Directly Promotes CGRP Release from Vagal Afferents in the Mouse
por: Jia, Lin, et al.
Publicado: (2021)

Afferent Loop Syndrome Due to Volvulus of the Afferent Limb
por: Desai, Aditi, et al.
Publicado: (2019)

Laser-evoked cortical responses in freely-moving rats reflect the activation of C-fibre afferent pathways
por: Xia, X.L., et al.
Publicado: (2016)

Renal Afferents
por: Frame, Alissa A., et al.
Publicado: (2016)

Fine-tuning of cortical progenitor proliferation by thalamic afferents
por: Gerstmann, Katrin, et al.
Publicado: (2015)

SYNAPTIC COMPONENTS OF CEREBELLAR ELECTROCORTICAL ACTIVITY EVOKED BY VARIOUS AFFERENT PATHWAYS
por: Purpura, D. P., et al.
Publicado: (1959)

The distribution and reliability of TMS-evoked short- and long-latency afferent interactions
por: Toepp, Stephen L., et al.
Publicado: (2021)

Optimized Measurement Parameters of Sensory Evoked Cortical Potentials to Assess Human Bladder Afferents - A Randomized Study
por: van der Lely, Stéphanie, et al.
Publicado: (2019)

ATP-sensitive muscle afferents activate spinal trigeminal neurons with meningeal afferent input in rat – pathophysiological implications for tension-type headache
por: Nöbel, Moritz, et al.
Publicado: (2016)

4096 Refined structure of human ferroportin using restraints from mass spectrometry
por: Parry, Christian S., et al.
Publicado: (2020)

Cortical Presynaptic Control of Dorsal Horn C–Afferents in the Rat
por: Moreno-López, Yunuen, et al.
Publicado: (2013)

In the back of your mind: Cortical mapping of paraspinal afferent inputs
por: Cole, David M., et al.
Publicado: (2022)

Optogenetic silencing of nociceptive primary afferents reduces evoked and ongoing bladder pain
por: Samineni, Vijay K., et al.
Publicado: (2017)

Experimentally Induced Bladder Permeability Evokes Bladder Afferent Hypersensitivity in the Absence of Inflammation
por: Grundy, Luke, et al.
Publicado: (2020)

The Transmission of Afferent Impulses
Publicado: (1909)

Dystrophin is expressed in smooth muscle and afferent nerve fibers in the rat urinary bladder
por: Lionarons, Judith M., et al.
Publicado: (2019)

Cerebral, subcortical, and cerebellar activation evoked by selective stimulation of muscle and cutaneous afferents: an fMRI study
por: Wardman, Daniel L., et al.
Publicado: (2014)

Brainstem Associated Somatosensory Evoked Potentials and Response to Vagus Nerve Stimulation: An Investigation of the Vagus Afferent Network
por: Suresh, Hrishikesh, et al.
Publicado: (2022)

Convergence across Tactile Afferent Types in Primary and Secondary Somatosensory Cortices
por: Carter, Andrew W., et al.
Publicado: (2014)

Whole-Brain Mapping of Monosynaptic Afferent Inputs to Cortical CRH Neurons
por: Zhang, Shouhua, et al.
Publicado: (2019)

Afterdischarges of Spinal Interneurons Following a Brief High-Frequency Stimulation of Ia Afferents in the Cat
por: Méndez-Fernández, Abraham, et al.
Publicado: (2020)

Muscular Afferents and Motor Control
por: Hunt, Carlton C.
Publicado: (1966)

Afferent Connectivity of the Zebrafish Habenulae
por: Turner, Katherine J., et al.
Publicado: (2016)

Afferents of the mouse linear nucleus
por: Liang, Huazheng, et al.
Publicado: (2020)

The Mysteries of Capsaicin-Sensitive Afferents
por: Fischer, Michael J. M., et al.
Publicado: (2020)

Migraine-relevant sex-dependent activation of mouse meningeal afferents by TRPM3 agonists
por: Krivoshein, G., et al.
Publicado: (2022)

Elucidating afferent-driven presynaptic inhibition of primary afferent input to spinal laminae I and X
por: Krotov, Volodymyr, et al.
Publicado: (2023)

Cortical spreading depression and meningeal nociception
por: Carneiro-Nascimento, Simone, et al.
Publicado: (2022)

Temperature Differentially Facilitates Spontaneous but Not Evoked Glutamate Release from Cranial Visceral Primary Afferents
por: Fawley, Jessica A., et al.
Publicado: (2015)

Thalamic afferents to prefrontal cortices from ventral motor nuclei in decision‐making
por: Sieveritz, Bianca, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_949vm3lkf8lg1ijl1302erncbv