Environmental toxin acrolein alters levels of endogenous lipids, including TRP agonists: A potential mechanism for headache driven by TRPA1 activation

Exposure to airborne toxins can trigger headaches, but the mechanisms are not well understood. Some environmental toxins, such as acrolein, activate transient receptor potential ankyrin 1 (TRPA1), a receptor involved in pain sensation that is highly expressed in the trigeminovascular system. It has...

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Detalles Bibliográficos
Autores principales: Leishman, Emma, Kunkler, Phillip E., Manchanda, Meera, Sangani, Kishan, Stuart, Jordyn M., Oxford, Gerry S., Hurley, Joyce H., Bradshaw, Heather B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802349/
https://www.ncbi.nlm.nih.gov/pubmed/29430557
http://dx.doi.org/10.1016/j.ynpai.2017.03.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802349/
https://www.ncbi.nlm.nih.gov/pubmed/29430557
http://dx.doi.org/10.1016/j.ynpai.2017.03.001

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