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Environmental toxin acrolein alters levels of endogenous lipids, including TRP agonists: A potential mechanism for headache driven by TRPA1 activation
Exposure to airborne toxins can trigger headaches, but the mechanisms are not well understood. Some environmental toxins, such as acrolein, activate transient receptor potential ankyrin 1 (TRPA1), a receptor involved in pain sensation that is highly expressed in the trigeminovascular system. It has...
Autores principales: | Leishman, Emma, Kunkler, Phillip E., Manchanda, Meera, Sangani, Kishan, Stuart, Jordyn M., Oxford, Gerry S., Hurley, Joyce H., Bradshaw, Heather B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802349/ https://www.ncbi.nlm.nih.gov/pubmed/29430557 http://dx.doi.org/10.1016/j.ynpai.2017.03.001 |
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