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Altered avalanche dynamics in a developmental NMDAR hypofunction model of cognitive impairment

Disturbed activity patterns in cortical networks contribute to the pathophysiology of schizophrenia (SZ). Several lines of evidence implicate NMDA receptor hypofunction in SZ, and blocking NMDA receptor signaling during early neurodevelopment produces cognitive deficits in rodent models that resembl...

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Detalles Bibliográficos
Autores principales: Seshadri, Saurav, Klaus, Andreas, Winkowski, Daniel E., Kanold, Patrick O., Plenz, Dietmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802445/
https://www.ncbi.nlm.nih.gov/pubmed/29317600
http://dx.doi.org/10.1038/s41398-017-0060-z