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Altered avalanche dynamics in a developmental NMDAR hypofunction model of cognitive impairment
Disturbed activity patterns in cortical networks contribute to the pathophysiology of schizophrenia (SZ). Several lines of evidence implicate NMDA receptor hypofunction in SZ, and blocking NMDA receptor signaling during early neurodevelopment produces cognitive deficits in rodent models that resembl...
Autores principales: | Seshadri, Saurav, Klaus, Andreas, Winkowski, Daniel E., Kanold, Patrick O., Plenz, Dietmar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802445/ https://www.ncbi.nlm.nih.gov/pubmed/29317600 http://dx.doi.org/10.1038/s41398-017-0060-z |
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