Treatment of bipolar depression with minocycline and/or aspirin: an adaptive, 2×2 double-blind, randomized, placebo-controlled, phase IIA clinical trial

Given evidence of chronic inflammation in bipolar disorder (BD), we tested the efficacy of aspirin and minocycline as augmentation therapy for bipolar depression. Ninety-nine depressed outpatients with BD were enrolled in a 6 week, double-blind, placebo-controlled trial, and randomized to one of fou...

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Detalles Bibliográficos
Autores principales: Savitz, Jonathan B., Teague, T. Kent, Misaki, Masaya, Macaluso, Matt, Wurfel, Brent E., Meyer, Matt, Drevets, Douglas, Yates, William, Gleason, Ondria, Drevets, Wayne C., Preskorn, Sheldon H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802452/
https://www.ncbi.nlm.nih.gov/pubmed/29362444
http://dx.doi.org/10.1038/s41398-017-0073-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802452/
https://www.ncbi.nlm.nih.gov/pubmed/29362444
http://dx.doi.org/10.1038/s41398-017-0073-7

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