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Genetic estimators of DNA methylation provide insights into the molecular basis of polygenic traits

The large biological distance between genetic risk loci and their mechanistic consequences in the tissue of interest limits the ability to establish functionality of susceptibility variants for genetically complex traits. Such a biological gap may be reduced through the systematic study of molecular...

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Detalles Bibliográficos
Autores principales: Freytag, Virginie, Vukojevic, Vanja, Wagner-Thelen, Holger, Milnik, Annette, Vogler, Christian, Leber, Markus, Weinhold, Leonie, Böhmer, Anne C., Riedel-Heller, Steffi, Maier, Wolfgang, de Quervain, Dominique J.-F., Ramirez, Alfredo, Papassotiropoulos, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802460/
https://www.ncbi.nlm.nih.gov/pubmed/29382824
http://dx.doi.org/10.1038/s41398-017-0070-x