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Polymorphism in Tmem132d regulates expression and anxiety-related behavior through binding of RNA polymerase II complex

TMEM132D is a candidate gene, where risk genotypes have been associated with anxiety severity along with higher mRNA expression in the frontal cortex of panic disorder patients. Concurrently, in a high (HAB) and low (LAB) trait anxiety mouse model, Tmem132d was found to show increased expression in...

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Detalles Bibliográficos
Autores principales: Naik, Roshan R., Sotnikov, Sergey V., Diepold, Rebekka P., Iurato, Stella, Markt, Patrick O., Bultmann, Andrea, Brehm, Nadine, Mattheus, Tobias, Lutz, Beat, Erhardt, Angelika, Binder, Elisabeth B., Schmidt, Ulrike, Holsboer, Florian, Landgraf, Rainer, Czibere, Ludwig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802467/
https://www.ncbi.nlm.nih.gov/pubmed/29317594
http://dx.doi.org/10.1038/s41398-017-0025-2