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Organoids with cancer stem cell-like properties secrete exosomes and HSP90 in a 3D nanoenvironment

Ability to form cellular aggregations such as tumorspheres and spheroids have been used as a morphological marker of malignant cancer cells and in particular cancer stem cells (CSC). However, the common definition of the types of cellular aggregation formed by cancer cells has not been available. We...

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Detalles Bibliográficos
Autores principales: Eguchi, Takanori, Sogawa, Chiharu, Okusha, Yuka, Uchibe, Kenta, Iinuma, Ryosuke, Ono, Kisho, Nakano, Keisuke, Murakami, Jun, Itoh, Manabu, Arai, Kazuya, Fujiwara, Toshifumi, Namba, Yuri, Murata, Yoshiki, Ohyama, Kazumi, Shimomura, Manami, Okamura, Hirohiko, Takigawa, Masaharu, Nakatsura, Tetsuya, Kozaki, Ken-ichi, Okamoto, Kuniaki, Calderwood, Stuart K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802492/
https://www.ncbi.nlm.nih.gov/pubmed/29415026
http://dx.doi.org/10.1371/journal.pone.0191109