TNFα depleting therapy improves fertility and animal welfare in TNFα-driven transgenic models of polyarthritis when administered in their routine breeding

Transgenic tumour necrosis factor alpha (TNFα)-driven models of polyarthritis such as the TNF(ΔARE) mouse have proven to be invaluable in delineating aspects of inflammatory disease pathophysiology in humans. Unfortunately, the onset of joint destruction and inflammation in these models represents a...

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Detalles Bibliográficos
Autores principales: Naylor, Amy J., Desanti, Guillaume, Saghir, Atif N., Hardy, Rowan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802519/
https://www.ncbi.nlm.nih.gov/pubmed/28480797
http://dx.doi.org/10.1177/0023677217707985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802519/
https://www.ncbi.nlm.nih.gov/pubmed/28480797
http://dx.doi.org/10.1177/0023677217707985

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