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Minimal residual disease by either flow cytometry or cytogenetics prior to an allogeneic hematopoietic stem cell transplant is associated with poor outcome in acute myeloid leukemia

Relapsed acute myeloid leukemia (AML) is a significant challenge after allogeneic hematopoietic cell transplant (HCT). Multiparameter flow cytometry (MFC), conventional cytogenetics (CG), and fluorescence in situ hybridization (FISH) are routinely performed on bone marrow specimens prior to HCT to a...

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Detalles Bibliográficos
Autores principales: Norkin, Maxim, Katragadda, Lakshmikanth, Zou, Fei, Xiong, Sican, Chang, Myron, Dai, Yunfeng, Hsu, Jack W., Moreb, Jan S., Leather, Helen, Murthy, Hemant S., Farhadfar, Nosha, Li, Ying, Hromas, Robert, Brown, Randy A., Cogle, Christopher R., Wingard, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802525/
https://www.ncbi.nlm.nih.gov/pubmed/29176662
http://dx.doi.org/10.1038/s41408-017-0007-x