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Enrichment of schizophrenia heritability in both neuronal and glia cell regulatory elements

Genome-wide association studies have identified over 100 robust risk loci for schizophrenia with thousands of variants mediating genetic heritability, the majority of which reside in non-coding regions. Analytical approaches have shown this heritability is strongly enriched at variants within regula...

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Detalles Bibliográficos
Autores principales: Tansey, Katherine E., Hill, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802526/
https://www.ncbi.nlm.nih.gov/pubmed/29317610
http://dx.doi.org/10.1038/s41398-017-0053-y