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A polygenic score for schizophrenia predicts glycemic control

Schizophrenia is substantially comorbid with type 2 diabetes (T2D), but the molecular basis of this effect is incompletely understood. Here, we show that a cortical schizophrenia expression score predicts glycemic control from pancreatic islet cell expression. We used machine learning to identify a...

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Detalles Bibliográficos
Autores principales: Cao, Han, Chen, Junfang, Meyer-Lindenberg, Andreas, Schwarz, Emanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802590/
https://www.ncbi.nlm.nih.gov/pubmed/29249829
http://dx.doi.org/10.1038/s41398-017-0044-z