Divergent effects of acute and repeated quetiapine treatment on dopamine neuron activity in normal vs. chronic mild stress induced hypodopaminergic states

Clinical evidence supports the use of second-generation dopamine D2 receptor antagonists (D2RAs) as adjunctive therapy or in some cases monotherapy in patients with depression. However, the mechanism for the clinical antidepressant effect of D2RAs remains unclear. Specifically, given accumulating ev...

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Detalles Bibliográficos
Autores principales: Moreines, Jared L., Owrutsky, Zoe L., Gagnon, Kimberly G., Grace, Anthony A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802622/
https://www.ncbi.nlm.nih.gov/pubmed/29225337
http://dx.doi.org/10.1038/s41398-017-0039-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802622/
https://www.ncbi.nlm.nih.gov/pubmed/29225337
http://dx.doi.org/10.1038/s41398-017-0039-9

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