Cargando…
Divergent effects of acute and repeated quetiapine treatment on dopamine neuron activity in normal vs. chronic mild stress induced hypodopaminergic states
Clinical evidence supports the use of second-generation dopamine D2 receptor antagonists (D2RAs) as adjunctive therapy or in some cases monotherapy in patients with depression. However, the mechanism for the clinical antidepressant effect of D2RAs remains unclear. Specifically, given accumulating ev...
Autores principales: | Moreines, Jared L., Owrutsky, Zoe L., Gagnon, Kimberly G., Grace, Anthony A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802622/ https://www.ncbi.nlm.nih.gov/pubmed/29225337 http://dx.doi.org/10.1038/s41398-017-0039-9 |
Ejemplares similares
-
Cannabis-Induced Hypodopaminergic Anhedonia and Cognitive Decline in Humans: Embracing Putative Induction of Dopamine Homeostasis
por: Blum, Kenneth, et al.
Publicado: (2021) -
Hypodopaminergic state of the nigrostriatal pathway drives compulsive alcohol use
por: Goutaudier, Raphaël, et al.
Publicado: (2022) -
Protracted Abstinence From Extended Cocaine Self-Administration Is Associated With Hypodopaminergic Activity in the VTA but Not in the SNc
por: Salin, Adélie, et al.
Publicado: (2020) -
Common Neurogenetic Diagnosis and Meso-Limbic Manipulation of Hypodopaminergic Function in Reward Deficiency Syndrome (RDS): Changing the Recovery Landscape
por: Blum, Kenneth, et al.
Publicado: (2017) -
Mechanisms of Sleep/Wake Regulation under Hypodopaminergic State: Insights from MitoPark Mouse Model of Parkinson's Disease
por: Fifel, Karim, et al.
Publicado: (2022)