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Possible role of the gut microbiota–brain axis in the antidepressant effects of (R)-ketamine in a social defeat stress model

Accumulating evidence suggests that the gut microbiota–brain axis plays a role in the pathogenesis of depression, thereby contributing to the antidepressant actions of certain compounds. (R)-ketamine has a greater potency and longer-lasting antidepressant effects than (S)-ketamine. Here, we investig...

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Detalles Bibliográficos
Autores principales: Yang, Chun, Qu, Youge, Fujita, Yuko, Ren, Qian, Ma, Min, Dong, Chao, Hashimoto, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802627/
https://www.ncbi.nlm.nih.gov/pubmed/29249803
http://dx.doi.org/10.1038/s41398-017-0031-4