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Proliferation dynamics of acute myeloid leukaemia and haematopoietic progenitors competing for bone marrow space

Leukaemia progressively invades bone marrow (BM), outcompeting healthy haematopoiesis by mechanisms that are not fully understood. Combining cell number measurements with a short-timescale dual pulse labelling method, we simultaneously determine the proliferation dynamics of primitive haematopoietic...

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Detalles Bibliográficos
Autores principales: Akinduro, O., Weber, T. S., Ang, H., Haltalli, M. L. R., Ruivo, N., Duarte, D., Rashidi, N. M., Hawkins, E. D., Duffy, K. R., Lo Celso, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802720/
https://www.ncbi.nlm.nih.gov/pubmed/29410432
http://dx.doi.org/10.1038/s41467-017-02376-5