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Proliferation dynamics of acute myeloid leukaemia and haematopoietic progenitors competing for bone marrow space
Leukaemia progressively invades bone marrow (BM), outcompeting healthy haematopoiesis by mechanisms that are not fully understood. Combining cell number measurements with a short-timescale dual pulse labelling method, we simultaneously determine the proliferation dynamics of primitive haematopoietic...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802720/ https://www.ncbi.nlm.nih.gov/pubmed/29410432 http://dx.doi.org/10.1038/s41467-017-02376-5 |