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Involvement of PKA/DARPP-32/PP1α and β- arrestin/Akt/GSK-3β Signaling in Cadmium-Induced DA-D2 Receptor-Mediated Motor Dysfunctions: Protective Role of Quercetin

Given increasing risk of cadmium-induced neurotoxicity, the study was conducted to delineate the molecular mechanisms associated with cadmium-induced motor dysfunctions and identify targets that govern dopaminergic signaling in the brain involving in vivo, in vitro, and in silico approaches. Selecti...

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Detalles Bibliográficos
Autores principales: Gupta, Richa, Shukla, Rajendra K., Pandey, Ankita, Sharma, Tanuj, Dhuriya, Yogesh K., Srivastava, Pranay, Singh, Manjul P., Siddiqi, Mohammad Imran, Pant, Aditya B., Khanna, Vinay K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802731/
https://www.ncbi.nlm.nih.gov/pubmed/29410441
http://dx.doi.org/10.1038/s41598-018-20342-z