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Knockdown of SPRY4 and SPRY4-IT1 inhibits cell growth and phosphorylation of Akt in human testicular germ cell tumours

Testicular germ cell tumour (TGCT) is the most common cancer in young men in large parts of the world, but the aetiology is mainly unknown. Genome-wide association studies have so far identified about 50 susceptibility loci associated with TGCT, including SPRY4. SPRY4 has shown tumour suppressor act...

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Detalles Bibliográficos
Autores principales: Das, Mrinal K., Furu, Kari, Evensen, Herman F., Haugen, Øyvind P., Haugen, Trine B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802735/
https://www.ncbi.nlm.nih.gov/pubmed/29410498
http://dx.doi.org/10.1038/s41598-018-20846-8