Crystal structure reveals vaccine elicited bactericidal human antibody targeting a conserved epitope on meningococcal fHbp

Data obtained recently in the United Kingdom following a nationwide infant immunization program against serogroup B Neisseria meningitidis (MenB) reported >80% 4CMenB vaccine-mediated protection. Factor H-binding protein (fHbp) is a meningococcal virulence factor and a component of two new MenB v...

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Detalles Bibliográficos
Autores principales: López-Sagaseta, Jacinto, Beernink, Peter T., Bianchi, Federica, Santini, Laura, Frigimelica, Elisabetta, Lucas, Alexander H., Pizza, Mariagrazia, Bottomley, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802752/
https://www.ncbi.nlm.nih.gov/pubmed/29410413
http://dx.doi.org/10.1038/s41467-018-02827-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802752/
https://www.ncbi.nlm.nih.gov/pubmed/29410413
http://dx.doi.org/10.1038/s41467-018-02827-7

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