The FDA-approved anti-cancer drugs, streptozotocin and floxuridine, reduce the virulence of Staphylococcus aureus

In Staphylococcus aureus, an important Gram-positive human pathogen, the SaeRS two-component system is essential for the virulence and a good target for the development of anti-virulence drugs. In this study, we screened 12,200 small molecules for Sae inhibitors and identified two anti-cancer drugs,...

Descripción completa

Detalles Bibliográficos
Autores principales: Yeo, Won-Sik, Arya, Rekha, Kim, Kyeong Kyu, Jeong, Hyunyoung, Cho, Kyu Hong, Bae, Taeok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802796/
https://www.ncbi.nlm.nih.gov/pubmed/29410445
http://dx.doi.org/10.1038/s41598-018-20617-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802796/
https://www.ncbi.nlm.nih.gov/pubmed/29410445
http://dx.doi.org/10.1038/s41598-018-20617-5

Ejemplares similares