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The FDA-approved anti-cancer drugs, streptozotocin and floxuridine, reduce the virulence of Staphylococcus aureus

In Staphylococcus aureus, an important Gram-positive human pathogen, the SaeRS two-component system is essential for the virulence and a good target for the development of anti-virulence drugs. In this study, we screened 12,200 small molecules for Sae inhibitors and identified two anti-cancer drugs,...

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Detalles Bibliográficos
Autores principales:	Yeo, Won-Sik, Arya, Rekha, Kim, Kyeong Kyu, Jeong, Hyunyoung, Cho, Kyu Hong, Bae, Taeok
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802796/ https://www.ncbi.nlm.nih.gov/pubmed/29410445 http://dx.doi.org/10.1038/s41598-018-20617-5

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